基本信息
姓名: 寿旦 性别: 女
学历: 本科 学位: 博士(博导)
职称: 研究员 出生年份: 1973
博导类型: 学术型 博导专业: 中药学 博导学院: 药学院
硕导类型: 硕导专业: 药物分析 硕导学院: 药学院
Email: shoudanok@163.com 联系电话: 0571
研究方向: 中药分析与质量评价，中药促进骨修复药效物质
工作单位: 浙江中医药大学药学院
发表论文

1、Benefits and mechanisms of polysaccharides from Chinese medicinal herbs for Anti-Osteoporosis Therapy: A Review,雷珊珊,寿旦（共同）,International Journal of Biological Macromolecules,SCI,2021-02,浙江省中医药研究院,2区,6.953,1996-2005

2、Erxian herbal pair enhances bone formation in osteomyelitis rabbits and attenuates (LPS)-induced osteoblast inhibition by regulating miR-34a-5p,张丽,寿旦（共同）,Bioengineered,SCI,2022-07,浙江中医药大学,3区,6.832,DOI: 10.1080/21655979.2022.2085388
3、Timosaponin AIII attenuates inflammatory injury in AGEs-induced osteoblast via modulating the RAGE/MAPK signaling pathways,王娜妮,寿旦（共同）,Phytomedicine,SCI,2020-05,浙江省中医药研究院,2区,5.340,153247
4、Timosaponin BII improved osteoporosis caused by hyperglycemia through promoting autophagy of osteoblasts via suppressing mTOR/NFκB signaling pathway,王娜妮,寿旦（共同）,Free Radical Biology and Medicine,SCI,2020-08,浙江省中医药研究院,2区,7.376,112-123
5、Transcriptome sequencing profiling identifies miRNA-331-3p as an osteoblast-specific miRNA in infected bone nonunion,张扬,寿旦（共同）,Bone,SCI,2021-01,浙江大学,2区,4.398,115619
6、Preparation of micro-cell membrane chromatographic columns with polyvinyl alcohol-modified polyether ether ketone tube as cellular membrane carrier,王娜妮,寿旦,Journal of Chromatography B,SCI,2019-01,浙江省中医药研究院,3区,2.813,102-108
7、Establishment of an improved rabbit model of bone infection with Staphylococcus aureus at tibia site and evaluation of combined treatment with vancomycin loaded calcium sulfate and autogenous bone,张扬,寿旦,Jove-Journal of Visualized Experiment,SCI,2019-03,浙江省中医药研究院,4区,1.108,doi: 10.3791/57294
8、Integrated pathological cell fishing and network pharmacology approach to investigate main active components of Er-Xian Decotion for treating osteoporosis,王娜妮,寿旦,Journal of Ethnopharmacology,SCI,2019-09,浙江省中医药研究院,3区,2.813,111977
9、Absorption and utilisation of epimedin C and icariin from Epimedii herba, and the regulatory mechanism via the BMP2/ Runx2 signalling pathway,黄孝闻,寿旦,Biomedicine & Pharmacotherapy,SCI,2019-10,浙江省中医药研究院,3区,3.743,109345
10、Construction of pH-responsive drug delivery platform with calcium carbonate microspheres induced by chitosan gels,Jingwei Wang,寿旦（共同，排名第二）,Ceramics International,SCI,2018-05,常州大学,2区,3.057,7902-7907
11、Comparative metabolites profiles of osthole in normal and osteoporosis rats using liquid chromatography/time-of-light mass spectormetry,王娜妮,寿旦（共同，排名第一）,Journal of Pharmaceutical and Biomedical Analysis,SCI,2018-05,浙江省中医药研究院,3区,2.831,460-467
12、Effects of alkaloids from Sophora flavescens on osteoblasts infected with Staphylococcus aureus and osteoclasts,王绪平,寿旦,Phytotheraphy Research,SCI,2018-06,浙江省中医药研究院,3区,3.349,1354-1363
13、Carbon nanotube-polymer composite for effervescent pipette tip solid phase microextraction of alkaloids and flavonoids from Epimedii herba in biological samples,王娜妮,寿旦（共同，排名第二）,Talata,SCI,2017-01,二军大,2区,4.162,10-18
14、淫羊藿-仙茅药对中6种成分的含量测定方法及配伍影响研究,许平翠,寿旦,中药材,中文，国内一级,2017-11,浙江中医药大学,,,2612-2615
15、Flavonoids of Herba Epimedii enhances bone repair in a rabbit model of chronic osteomyelitis during post-infection treatment and stimulates osteoblast proliferation in vitro,寿旦,寿旦,Pytotherapy Research,SCI,2017-02,浙江大学,3区,3.092,330-339
16、Efficient induction of antimicrobial activity with vancomycin nanoparticles loaded poly-(trimethylene carbonate) localized drug delivery system,张扬,寿旦（共同，排名第一）,International Journal of Nanomedicine,SCI,2019-02,浙江省中医药研究院,2区,4.300,1201-1214
17、Core-shell structured polypyrrole/mesoporous SiO2 nanocomposite capped with graphene quantum dots as gratekeeper for irradiation-controlled release of methotrexate,Xiaolin Liu,寿旦（共同，排名第二）,Materials Science & Engineering C,SCI,2017-11,常州大学,1区,4.164,102-108
18、Cariin enhances bone repair in a rabbit model of chronic osteomyelitis during post-infection treatment and resists inhibition of vancomycin on osteoblasts,张扬,寿旦（共同，排名第一）,Frontiers in pharmacology,SCI,2017-10,浙江省中医药研究院,2区,4.400,doi: 10.3389/fphar.2017.00784
19、炮制工艺对白术挥发油组成及3种白术内酯含量的影响研究,费莹,寿旦,中华中医药学刊,中文，国内一级,2016-02,浙江中医药大学,,,418-421
20、Rapid Quantification of Tobramycin and Vancomycin by UPLC–TQD and Application to Osteomyelitis Patient Samples,寿旦,寿旦,Journal of Chromatographic Science,SCI,2014-06,浙江省中医药研究院,3区,1.026,501-507
21、Effects of Sanguis Draconis on Perforator Flap Survival in Rats,张扬,寿旦,Molecules,SCI,2016-10,浙江省中医药研究院,3区,2.465,doi:10.3390/molecules21101262
科研项目

1、治疗牙周炎经典名方-玉女煎的物质基准研究及颗粒剂研发,寿旦,浙江省中医药研究院,省科技厅,省部级,2021-01,2023-12,130,190

2、白术等14种中药饮片标准化体系及追溯系统建设,寿旦（分任务负责人）,北京华邈药业有限公司,国家中医药管理局,省部级,2016-01,2018-12,45,0.00
3、补肾中药治疗慢性骨髓炎骨不连的作用及经BMP2/Smads/Runx2通路的调控机制,寿旦,浙江省中医药研究院,省科技厅,省部级,2016-01,2018-12,20,0.00
4、基于微流控芯片技术的慢性骨髓炎微环境及淫羊藿促骨修复机制研究,寿旦,浙江省中医药研究院,省科技厅,省部级,2016-10,2019-12,9,0.00
5、二仙药对影响miRNA-34/lncRNA PINK1-AS1互作调控BMP-2/Runx2通路促进慢性骨髓炎骨修复的机制研究,寿旦,浙江省中医药研究院,国家基金委,国家级,2018-08,2020-12,25,0.00
6、“十三五”省中医药重点学科-中药与天然药物分析学,寿旦,浙江省立同德医院,浙江省中管局,厅局级,2017-10,2020-12,30,90
7、浙江省卫生高层次人才-创新人才,寿旦,浙江省立同德医院,浙江省卫计委,厅局级,2014-09,2019-12,40,40
8、浙江省151人才工程第二层次,寿旦,浙江省立同德医院,浙江省人社厅,厅局级,2016-11,2021-12,4,4
9、“浙八味”道地药材配方颗粒的产业链全程质量控制体系研究,寿旦,浙江省立同德医院,浙江省中管局,厅局级,2017-09,2022-08,50,50
科研成果

1、中药分析新技术在浙产特色药材质量控制中的应用,寿旦,1,浙江省中医药研究院,浙江省科技进步奖二等奖,省部级,2018-05

2、体外模拟法优化骨髓炎载抗生素人工骨治疗方案的实验研究,寿旦,1,浙江省立同德医院,浙江省科技进步奖三等奖,省部级,2015-05
3、桑黄功效作用研究及人工栽培质量控制体系的建立,寿旦,1,浙江省中医药研究院,浙江省中医药科学技术奖一等奖,厅局级,2017-04
4、电调控色谱固定相的研制及其在手性药物拆分中的应用,寿旦,3/8,常州大学,中国商业联合会科学技术奖二等奖,省部级,2016-12
5、天然多糖复合凝胶的开发及在药物控释中的应用,寿旦,3/10,常州大学,中国商业联合会科学技术奖三等奖,省部级,2017-12
个人信息

博士，研究员，浙江省151人才第二层次培养对象，浙江省卫生创新人才，浙江省“十三五”中医药重点学科负责人；任中华中医药学会中药化学分会等3个国家委员；浙江省中药材产业服务团队特色药材组副组长；“中国现代应用药学”期刊编委；10多个SCI期刊同行评阅专家。国家科技部专家库，国家奖励评审专家库专家。 研究方向为中药分析与质量评价，近10年还开展骨髓炎骨不连机制及中药应用研究。主持承担国家自然科学基金、国家中药标准化项目等国家级项目4项，省自然基金等省级项目12项。以一作/通讯作者发表论文90多篇（SCI收录34篇）；获发明专利7项；主持获浙江省科技进步奖二等奖、三等奖各1项，厅局级奖励5项，参与获得省部级奖励4项。负责制订多个中药复方（药材）及6个医疗机构新制剂的质量标准，起草了白术、薏苡仁等药材饮片等级标准草案；参与获得中药新药临床批件2项。已培养研究生6名，正在培养4名。